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Ace031 1mg x 1vial + 2ml Injection solvent ample


Ace031 1mg x 1vial + 2ml Injection solvent ample

ACVR2B (ACE-031) 1MG

ACE-031 1 dose of ACE-031 (0.02–3 mg/kg)

average half-life ranging from 10-15 days

Because the half-life is long, the injection can be experienced by injection of 1-2 mg once a week in many cases, but continuing injection once a week for 3-6 months, with Follistatin 344 It is used by alternating 10-day cycles and so on.

Activin receptor type-2B is a protein that in humans is encoded by the ACVR2B gene. ACVR2B is an activin type 2 receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

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